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The key point of this concept is the deliberate use of samples that contain 13C at its natural isotopic abundance (NA, 1.1%), while exploiting magic angle spinning dynamic nuclear polarization (MAS DNP) to compensate for the reduced sensitivity. Since dipolar truncation effects are suppressed to a large extent in NA samples, unique and highly informative spectra can be recorded which… Read more →

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Infective endocarditisA diagnosis of infective endocarditis can be obtained through patient history, EKG, ultrasound, or cardiac catheterization. Patients who have developed the disease rapidly may report fever, fatigue, night sweats, chills, and joint inflammation. Those whose disease has developed more slowly will show signs of rapid heart rate, an enlarged spleen, various skin colors or spots, and heart murmur. Right,… Read more →

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Here we describe a methoxy poly(ethyleneglycol) b poly( decalactone) (mPEG b PDL) copolymer and investigate the potential of the copolymer as a vehicle for solubilisation and sustained release of indomethacin (IND). The indomethacin loading and release from mPEG b PDL micelles (amorphous cores) was compared against methoxy poly(ethyleneglycol) b poly( caprolactone)(mPEG b PCL) micelles (semicrystalline cores). The drug “polymer compatibility… Read more →

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Protected learning time (PLT) schemes have been set up in primary care across the UK. There is little published evidence of their effectiveness. To investigate the effect of a PLT intervention for general practice to increase prescribing of ramipril for prevention of cardiovascular outcomes. If there is one thing that Long Island is known for, it is our vast, beautiful… Read more →

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Is the world 11th biggest economy and the United States biggest trading partner. The Canadian economy suffered far less damage from the financial crisis and Great Recession than its southern neighbour. But news this month of a recession spelled trouble for Prime Minister Stephen Harper. On the other hand, if the two species are first partially self assembled (by partial… Read more →

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