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Protein transduction domains (PTDs) are powerful nongenetic tools that allow intracellular delivery of conjugated cargoes to modify cell behavior. Their use in biomedicine has been hampered by inefficient delivery to nuclear and cytoplasmic targets. Here we overcame this deficiency by developing a series of novel fusion proteins that couple a membrane docking peptide to heparan sulfate glycosaminoglycans (GAGs) with a… Read more →

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A number of papers in recent years have covered specific aspects of the technology, including sensor design optimization, sensor characteristic analysis, signal de noising and practical applications of the technology. This paper provides a review of the recent research and of the development of electrostatic monitoring technology, with a primary emphasis on its application for the aero engine gas path.… Read more →

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CLEVELAND, Oh Looking for different recipe ideas for your Thanksgiving meal? Look no further than the wineries of the Grand River Valley. The annual Turkey Trot offers guests Thanksgiving themed appetizers along with wine pairings. Cindy Lindberg from Grand River Cellars Winery explains how it works to Fox 8’s Stefani Schaefer and also shares her recipe for the dish Grand… Read more →

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Cernan’s Apollo 17 lunar suit is currently on display at the Smithsonian National Air and Space Museum, just one of the 137 million Apollo era artifacts in the museum’s collection. Image Credit: National Air and Space MuseumThe fourth group brought a change. In June 1965, six trained scientists joined NASA’s astronaut corps. Actress has The Look. The original’s inked heroine,… Read more →